Cargando…

Lysine methyltransferase G9a is an important modulator of trained immunity

OBJECTIVES: Histone methyltransferase G9a, also known as Euchromatic Histone Lysine Methyltransferase 2 (EHMT2), mediates H3K9 methylation which is associated with transcriptional repression. It possesses immunomodulatory effects and is overexpressed in multiple types of cancer. In this study, we in...

Descripción completa

Detalles Bibliográficos
Autores principales: Mourits, Vera P, van Puffelen, Jelmer H, Novakovic, Boris, Bruno, Mariolina, Ferreira, Anaísa V, Arts, Rob JW, Groh, Laszlo, Crișan, Tania O, Zwaag, Jelle, Jentho, Elisa, Kox, Matthijs, Pickkers, Peter, van de Veerdonk, Frank L, Weis, Sebastian, Oosterwijk, Egbert, Vermeulen, Sita H, Netea, Mihai G, Joosten, Leo AB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890679/
https://www.ncbi.nlm.nih.gov/pubmed/33708384
http://dx.doi.org/10.1002/cti2.1253