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Ring finger protein 152-dependent degradation of TSPAN12 suppresses hepatocellular carcinoma progression

BACKGROUND: Hepatocellular carcinoma (HCC) is the third cause of cancer death in the world, and few molecularly targeted anticancer therapies have been developed to treat it. The E3 ubiquitin ligase RNF152 has been reported to regulate the activity of the mechanistic target of rapamycin complex 1 (m...

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Detalles Bibliográficos
Autores principales: Wan, Jian, Liu, Shunfang, Sun, Wanju, Yu, Haiyi, Tang, Wenlian, Liu, Wei, Ji, Jing, Liu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890835/
https://www.ncbi.nlm.nih.gov/pubmed/33602225
http://dx.doi.org/10.1186/s12935-021-01806-1