LINE retrotransposons characterize mammalian tissue-specific and evolutionarily dynamic regulatory regions

BACKGROUND: To investigate the mechanisms driving regulatory evolution across tissues, we experimentally mapped promoters, enhancers, and gene expression in the liver, brain, muscle, and testis from ten diverse mammals. RESULTS: The regulatory landscape around genes included both tissue-shared and t...

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Detalles Bibliográficos
Autores principales: Roller, Maša, Stamper, Ericca, Villar, Diego, Izuogu, Osagie, Martin, Fergal, Redmond, Aisling M., Ramachanderan, Raghavendra, Harewood, Louise, Odom, Duncan T., Flicek, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890895/
https://www.ncbi.nlm.nih.gov/pubmed/33602314
http://dx.doi.org/10.1186/s13059-021-02260-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890895/
https://www.ncbi.nlm.nih.gov/pubmed/33602314
http://dx.doi.org/10.1186/s13059-021-02260-y

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