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Diversity-oriented synthesis derived indole based spiro and fused small molecules kills artemisinin-resistant Plasmodium falciparum

BACKGROUND: Despite numerous efforts to eradicate the disease, malaria continues to remain one of the most dangerous infectious diseases plaguing the world. In the absence of any effective vaccines and with emerging drug resistance in the parasite against the majority of anti-malarial drugs, the sea...

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Detalles Bibliográficos
Autores principales: Nayak, Akshaykumar, Saxena, Himani, Bathula, Chandramohan, Kumar, Tarkeshwar, Bhattacharjee, Souvik, Sen, Subhabrata, Gupta, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891021/
https://www.ncbi.nlm.nih.gov/pubmed/33596950
http://dx.doi.org/10.1186/s12936-021-03632-2