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Toxicarioside O Inhibits Cell Proliferation and Epithelial-Mesenchymal Transition by Downregulation of Trop2 in Lung Cancer Cells

Toxicarioside O (TCO), a natural product derived from Antiaris toxicaria, has been identified to be a promising anticancer agent. In this study, we aimed to investigate the effect of TCO on the proliferation and epithelial-mesenchymal transition (EMT) of lung cancer cells and its molecular mechanism...

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Detalles Bibliográficos
Autores principales: Zheng, Wu-Ping, Huang, Feng-Ying, Dai, Shu-Zhen, Wang, Jin-Yan, Lin, Ying-Ying, Sun, Yan, Tan, Guang-Hong, Huang, Yong-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891104/
https://www.ncbi.nlm.nih.gov/pubmed/33614493
http://dx.doi.org/10.3389/fonc.2020.609275