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Bright fluorescent nucleic acid detection with CRISPR-Cas12a and poly(thymine) templated copper nanoparticles

Fluorescence-based diagnostic tools are attractive and versatile tests with multiple advantages: ease of use, sensitivity and rapid results. The advent of CRISPR-Cas technology has created new avenues for the development of diagnostic testing tools. In this study, by effectively combining the specif...

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Detalles Bibliográficos
Autores principales: Bogers, Janna F M, Berghuis, Nicole F, Busker, Ruud W, van Booma, Angelo, Paauw, Armand, van Leeuwen, Hans C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891128/
https://www.ncbi.nlm.nih.gov/pubmed/33628946
http://dx.doi.org/10.1093/biomethods/bpaa020