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Plectin dysfunction in neurons leads to tau accumulation on microtubules affecting neuritogenesis, organelle trafficking, pain sensitivity and memory

AIMS: Plectin, a universally expressed multi‐functional cytolinker protein, is crucial for intermediate filament networking, including crosstalk with actomyosin and microtubules. In addition to its involvement in a number of diseases affecting skin, skeletal muscle, heart, and other stress‐exposed t...

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Detalles Bibliográficos
Autores principales: Valencia, R. G., Mihailovska, E., Winter, L., Bauer, K., Fischer, I., Walko, G., Jorgacevski, J., Potokar, M., Zorec, R., Wiche, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891324/
https://www.ncbi.nlm.nih.gov/pubmed/32484610
http://dx.doi.org/10.1111/nan.12635