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Pharmacokinetic Comparison of Capsule and Tablet Formulations of Opicapone in Healthy Japanese Subjects: Phase 1 Study

Opicapone, a peripheral, long‐acting catechol‐O‐methyltransferase inhibitor has been shown to improve wearing‐off phenomenon in randomized, double‐blind studies. This study compared the pharmacokinetic characteristics of opicapone small‐tablet and size 1 capsule formulations after single oral admini...

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Detalles Bibliográficos
Autores principales: Nomoto, Masahiro, Takeda, Atsushi, Iwai, Katsuaki, Nishimura, Akihisa, Hattori, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891373/
https://www.ncbi.nlm.nih.gov/pubmed/32459885
http://dx.doi.org/10.1002/cpdd.802