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Selection of antimicrobial frog peptides and temporin‐1DRa analogues for treatment of bacterial infections based on their cytotoxicity and differential activity against pathogens

Cationic, amphipathic, α‐helical host‐defense peptides (HDPs) that are naturally secreted by certain species of frogs (Anura) possess potent broad‐spectrum antimicrobial activity and show therapeutic potential as alternatives to treat infections by multidrug‐resistant pathogens. Fourteen amphibian s...

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Detalles Bibliográficos
Autores principales: Gaiser, Rogier A., Ayerra Mangado, Jaione, Mechkarska, Milena, Kaman, Wendy E., van Baarlen, Peter, Conlon, J. Michael, Wells, Jerry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891380/
https://www.ncbi.nlm.nih.gov/pubmed/31102497
http://dx.doi.org/10.1111/cbdd.13569