Genome‐wide CRISPR screen identifies ZIC2 as an essential gene that controls the cell fate of early mesodermal precursors to human heart progenitors

Cardiac progenitor formation is one of the earliest committed steps of human cardiogenesis and requires the cooperation of multiple gene sets governed by developmental signaling cascades. To determine the key regulators for cardiac progenitor formation, we have developed a two‐stage genome‐wide CRIS...

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Detalles Bibliográficos
Autores principales: Xu, Jiejia, Zhou, Chikai, Foo, Kylie S., Yang, Ran, Xiao, Yao, Bylund, Kristine, Sahara, Makoto, Chien, Kenneth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Stem Cell Technology: Epigenetics, Genomics, Proteomics and Metabonomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891398/
https://www.ncbi.nlm.nih.gov/pubmed/32129551
http://dx.doi.org/10.1002/stem.3168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891398/
https://www.ncbi.nlm.nih.gov/pubmed/32129551
http://dx.doi.org/10.1002/stem.3168

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