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CFTR Correctors and Antioxidants Partially Normalize Lipid Imbalance but not Abnormal Basal Inflammatory Cytokine Profile in CF Bronchial Epithelial Cells

A deficiency in cystic fibrosis transmembrane conductance regulator (CFTR) function in CF leads to chronic lung disease. CF is associated with abnormalities in fatty acids, ceramides, and cholesterol, their relationship with CF lung pathology is not completely understood. Therefore, we examined the...

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Detalles Bibliográficos
Autores principales: Veltman, Mieke, De Sanctis, Juan B., Stolarczyk, Marta, Klymiuk, Nikolai, Bähr, Andrea, Brouwer, Rutger W., Oole, Edwin, Shah, Juhi, Ozdian, Tomas, Liao, Jie, Martini, Carolina, Radzioch, Danuta, Hanrahan, John W., Scholte, Bob J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891400/
https://www.ncbi.nlm.nih.gov/pubmed/33613309
http://dx.doi.org/10.3389/fphys.2021.619442