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Tryptophan Analogues with Fixed Side‐Chain Orientation: Expanding the Scope

A generalized synthetic strategy is proposed here for the synthesis of asymmetric β‐indoylated amino acids by 8‐aminoquinoline (8AQ)‐directed C(sp(3))‐H functionalization of suitably protected precursors. Peptides containing one of the four stereoisomers of (indol‐3‐yl)‐3‐phenylalanine at position 2...

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Detalles Bibliográficos
Autores principales: Nicke, Lennart, Horx, Philip, Müller, Ronny, Els‐Heindl, Sylvia, Geyer, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891422/
https://www.ncbi.nlm.nih.gov/pubmed/33463878
http://dx.doi.org/10.1002/cbic.202000424