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Memory B Cell Activation, Broad Anti-influenza Antibodies, and Bystander Activation Revealed by Single-Cell Transcriptomics

Antibody memory protects humans from many diseases. Protective antibody memory responses require activation of transcriptional programs, cell proliferation, and production of antigen-specific antibodies, but how these aspects of the response are coordinated is poorly understood. We profile the molec...

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Detalles Bibliográficos
Autores principales: Horns, Felix, Dekker, Cornelia L., Quake, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891556/
https://www.ncbi.nlm.nih.gov/pubmed/31968262
http://dx.doi.org/10.1016/j.celrep.2019.12.063