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Mendelian randomisation approaches to the study of prenatal exposures: A systematic review

BACKGROUND: Mendelian randomisation (MR) designs apply instrumental variable techniques using genetic variants to study causal effects. MR is increasingly used to evaluate the role of maternal exposures during pregnancy on offspring health. OBJECTIVES: We review the application of MR to prenatal exp...

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Detalles Bibliográficos
Autores principales: Diemer, Elizabeth W., Labrecque, Jeremy A., Neumann, Alexander, Tiemeier, Henning, Swanson, Sonja A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891574/
https://www.ncbi.nlm.nih.gov/pubmed/32779786
http://dx.doi.org/10.1111/ppe.12691