Effect of Opicapone Tablets on Levodopa and 3‐O‐Methyldopa Pharmacokinetics in Healthy Japanese Subjects: Phase 1 Study

This study evaluated the effect of a small‐tablet formulation of opicapone for use in clinical trials in Japan on the pharmacokinetics of levodopa (l‐dopa) and 3‐O‐methyldopa (3‐OMD). In an open‐label, 3‐period, single‐sequence crossover phase 1 study in 80 healthy Japanese males (aged 20‐45 years;...

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Detalles Bibliográficos
Autores principales: Nomoto, Masahiro, Takeda, Atsushi, Iwai, Katsuaki, Nishimura, Akihisa, Hattori, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891606/
https://www.ncbi.nlm.nih.gov/pubmed/32416054
http://dx.doi.org/10.1002/cpdd.799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891606/
https://www.ncbi.nlm.nih.gov/pubmed/32416054
http://dx.doi.org/10.1002/cpdd.799

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