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Drug sensitivity prediction with normal inverse Gaussian shrinkage informed by external data

In precision medicine, a common problem is drug sensitivity prediction from cancer tissue cell lines. These types of problems entail modelling multivariate drug responses on high‐dimensional molecular feature sets in typically >1000 cell lines. The dimensions of the problem require specialised mo...

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Detalles Bibliográficos
Autores principales: Münch, Magnus M., van de Wiel, Mark A., Richardson, Sylvia, Leday, Gwenaël G. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891636/
https://www.ncbi.nlm.nih.gov/pubmed/33155717
http://dx.doi.org/10.1002/bimj.201900371