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A simple novel approach for detecting blood–brain barrier permeability using GPCR internalization

AIMS: Impairment of blood–brain barrier (BBB) is involved in numerous neurological diseases from developmental to aging stages. Reliable imaging of increased BBB permeability is therefore crucial for basic research and preclinical studies. Today, the analysis of extravasation of exogenous dyes is th...

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Detalles Bibliográficos
Autores principales: Csaba, Z., Vitalis, T., Charriaut‐Marlangue, C., Margaill, I., Coqueran, B., Leger, P.‐L., Parente, I., Jacquens, A., Titomanlio, L., Constans, C., Demene, C., Santin, M. D., Lehericy, S., Perrière, N., Glacial, F., Auvin, S., Tanter, M., Ghersi‐Egea, J.‐F., Adle‐Biassette, H., Aubry, J.‐F., Gressens, P., Dournaud, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891648/
https://www.ncbi.nlm.nih.gov/pubmed/32898926
http://dx.doi.org/10.1111/nan.12665