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Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease

BACKGROUND AND AIMS: Polycystic liver diseases (PLDs) are genetic disorders characterized by progressive development of symptomatic biliary cysts. Current surgical and pharmacological approaches are ineffective, and liver transplantation represents the only curative option. Ursodeoxycholic acid (UDC...

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Detalles Bibliográficos
Autores principales: Caballero‐Camino, Francisco J., Rivilla, Ivan, Herraez, Elisa, Briz, Oscar, Santos‐Laso, Alvaro, Izquierdo‐Sanchez, Laura, Lee‐Law, Pui Y., Rodrigues, Pedro M., Munoz‐Garrido, Patricia, Jin, Sujeong, Peixoto, Estanislao, Richard, Seth, Gradilone, Sergio A., Perugorria, Maria J., Esteller, Manel, Bujanda, Luis, Marin, Jose J.G., Banales, Jesus M., Cossío, Fernando P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891670/
https://www.ncbi.nlm.nih.gov/pubmed/32145077
http://dx.doi.org/10.1002/hep.31216