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Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease
BACKGROUND AND AIMS: Polycystic liver diseases (PLDs) are genetic disorders characterized by progressive development of symptomatic biliary cysts. Current surgical and pharmacological approaches are ineffective, and liver transplantation represents the only curative option. Ursodeoxycholic acid (UDC...
Autores principales: | Caballero‐Camino, Francisco J., Rivilla, Ivan, Herraez, Elisa, Briz, Oscar, Santos‐Laso, Alvaro, Izquierdo‐Sanchez, Laura, Lee‐Law, Pui Y., Rodrigues, Pedro M., Munoz‐Garrido, Patricia, Jin, Sujeong, Peixoto, Estanislao, Richard, Seth, Gradilone, Sergio A., Perugorria, Maria J., Esteller, Manel, Bujanda, Luis, Marin, Jose J.G., Banales, Jesus M., Cossío, Fernando P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891670/ https://www.ncbi.nlm.nih.gov/pubmed/32145077 http://dx.doi.org/10.1002/hep.31216 |
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