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Saliva as a potential matrix for evaluating pharmacologically active dolutegravir concentration in plasma

Therapeutic drug monitoring (TDM) is used in certain clinically selected cases and in research settings to optimize the response to antiretroviral therapy. Plasma of blood is commonly used for TDM, but blood sampling is invasive and at risk for transmission of infectious agents. On the other hand, s...

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Detalles Bibliográficos
Autores principales: Yamada, Eiko, Takagi, Ritsuo, Moro, Hiroshi, Sudo, Koji, Kato, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891697/
https://www.ncbi.nlm.nih.gov/pubmed/33600473
http://dx.doi.org/10.1371/journal.pone.0246994