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Preclinical transmission of prions by blood transfusion is influenced by donor genotype and route of infection

Variant Creutzfeldt-Jakob disease (vCJD) is a human prion disease resulting from zoonotic transmission of bovine spongiform encephalopathy (BSE). Documented cases of vCJD transmission by blood transfusion necessitate on-going risk reduction measures to protect blood supplies, such as leucodepletion...

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Detalles Bibliográficos
Autores principales: Salamat, M. Khalid F., Blanco, A. Richard Alejo, McCutcheon, Sandra, Tan, Kyle B. C., Stewart, Paula, Brown, Helen, Smith, Allister, de Wolf, Christopher, Groschup, Martin H., Becher, Dietmar, Andréoletti, Olivier, Turner, Marc, Manson, Jean C., Houston, E. Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891701/
https://www.ncbi.nlm.nih.gov/pubmed/33600501
http://dx.doi.org/10.1371/journal.ppat.1009276