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Development of a program for in silico optimized selection of oligonucleotide-based molecular barcodes

Short DNA oligonucleotides (~4 mer) have been used to index samples from different sources, such as in multiplex sequencing. Presently, longer oligonucleotides (8–12 mer) are being used as molecular barcodes with which to distinguish among raw DNA molecules in many high-tech sequence analyses, inclu...

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Detalles Bibliográficos
Autores principales: Yang, In Seok, Bae, Sang Won, Park, BeumJin, Kim, Sangwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891705/
https://www.ncbi.nlm.nih.gov/pubmed/33600481
http://dx.doi.org/10.1371/journal.pone.0246354