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Modeling drug response using network-based personalized treatment prediction (NetPTP) with applications to inflammatory bowel disease
For many prevalent complex diseases, treatment regimens are frequently ineffective. For example, despite multiple available immunomodulators and immunosuppressants, inflammatory bowel disease (IBD) remains difficult to treat. Heterogeneity in the disease across patients makes it challenging to selec...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891788/ https://www.ncbi.nlm.nih.gov/pubmed/33544718 http://dx.doi.org/10.1371/journal.pcbi.1008631 |