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Downregulation of lncRNA MIR181A2HG by high glucose impairs vascular endothelial cell proliferation and migration through the dysregulation of the miRNAs/AKT2 axis
Endothelial dysfunction and diabetic vascular disease induced by chronic hyperglycemia involve complex interactions among high glucose, long non-coding RNAs (lncRNAs), microRNAs (miRNAs or miRs) and the Ser/Thr kinase AKT. However, the molecular mechanisms under-lying the regulatory crosstalk betwee...
Autores principales: | Wang, Shaohua, Zheng, Bin, Zhao, Hongye, Li, Yongjun, Zhang, Xinhua, Wen, Jinkun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891834/ https://www.ncbi.nlm.nih.gov/pubmed/33537821 http://dx.doi.org/10.3892/ijmm.2021.4868 |
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