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Helichrysetin and TNF-α synergistically promote apoptosis by inhibiting overactivation of the NF-κB and EGFR signaling pathways in HeLa and T98G cells

Tumor necrosis factor-α (TNF-α) has different effects on apoptosis depending on activation or inactivation of the nuclear factor-κB (NF-κB) and epidermal growth factor receptor (EGFR) signaling pathways. Helichrysetin, a natural chalcone, inhibits NF-κB nuclear translocation in mouse pancreatic β ce...

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Detalles Bibliográficos
Autores principales: Wang, Zhiying, Liang, Xiaohui, Xiong, Aizhen, Ding, Lili, Li, Wei, Yang, Li, Wu, Xiaojun, Shi, Hailian, Zhou, Yue, Wang, Zhengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891838/
https://www.ncbi.nlm.nih.gov/pubmed/33576459
http://dx.doi.org/10.3892/ijmm.2021.4882