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Downregulating Gasdermin D Reduces Severe Acute Pancreatitis Associated with Pyroptosis

BACKGROUND: Intestinal injury plays a key role in the pathogenesis of severe acute pancreatitis (SAP). In this study, we investigated the protective function of downregulated Gasdermin D (GSDMD) in intestinal damage in a mouse model of severe acute pancreatitis (SAP). MATERIAL/METHODS: Twenty-four h...

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Detalles Bibliográficos
Autores principales: Lin, Tianjiao, Song, Jingyu, Pan, Xinting, Wan, Youdong, Wu, Ziqian, Lv, Shaoyan, Mi, Liangyu, Wang, Yunyun, Tian, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891845/
https://www.ncbi.nlm.nih.gov/pubmed/33582700
http://dx.doi.org/10.12659/MSM.927968