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Bariatric surgery reveals a gut-restricted TGR5 agonist with anti-diabetic effects

Bariatric surgery, the most effective treatment for obesity and type 2 diabetes, is associated with increased levels of the incretin hormone GLP-1 and changes in levels of circulating bile acids. The levels of individual bile acids in the GI tract following surgery, however, have remained largely un...

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Detalles Bibliográficos
Autores principales: Chaudhari, Snehal N., Harris, David A., Aliakbarian, Hassan, Luo, James N., Henke, Matthew T., Subramaniam, Renuka, Vernon, Ashley H., Tavakkoli, Ali, Sheu, Eric G., Devlin, A. Sloan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891870/
https://www.ncbi.nlm.nih.gov/pubmed/32747812
http://dx.doi.org/10.1038/s41589-020-0604-z