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Intronic enhancer region governs transcript-specific Bdnf expression in rodent neurons

Brain-derived neurotrophic factor (BDNF) controls the survival, growth, and function of neurons both during the development and in the adult nervous system. Bdnf is transcribed from several distinct promoters generating transcripts with alternative 5' exons. Bdnf transcripts initiated at the fi...

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Detalles Bibliográficos
Autores principales: Tuvikene, Jürgen, Esvald, Eli-Eelika, Rähni, Annika, Uustalu, Kaie, Zhuravskaya, Anna, Avarlaid, Annela, Makeyev, Eugene V, Timmusk, Tõnis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891933/
https://www.ncbi.nlm.nih.gov/pubmed/33560226
http://dx.doi.org/10.7554/eLife.65161