Inhibition of CXCR2 alleviates the development of abdominal aortic aneurysm in Apo E(-/-) mice

PURPOSE: To investigate the relationship between atherosclerotic abdominal aortic aneurysm (AAA) and CXC chemokine receptor type 2 (CXCR2). METHODS: Mouse AAA model was established by embedding angiotensin-II pump (1000 ng/kg/min) in ApoE(-/-) mice. Mice were received SB225002, a selective CXCR2 ant...

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Detalles Bibliográficos
Autores principales: Sun, Bo, Li, Fangda, Lai, Song, Zhang, Xu, Wang, Hongxia, Li, Yuan, Wang, Wei, Chen, Yuexin, Liu, Bao, Zheng, Yuehong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892195/
https://www.ncbi.nlm.nih.gov/pubmed/33605308
http://dx.doi.org/10.1590/ACB360105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892195/
https://www.ncbi.nlm.nih.gov/pubmed/33605308
http://dx.doi.org/10.1590/ACB360105

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