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Loss and revival of androgen receptor signaling in advanced prostate cancer

Targeting the androgen receptor (AR) signaling axis has been, over decades, the mainstay of prostate cancer therapy. More potent inhibitors of androgen synthesis and antiandrogens have emerged and have been successfully implemented in clinical practice. That said, the stronger inhibition of the AR s...

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Detalles Bibliográficos
Autores principales: Formaggio, Nicolò, Rubin, Mark A., Theurillat, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892335/
https://www.ncbi.nlm.nih.gov/pubmed/33420371
http://dx.doi.org/10.1038/s41388-020-01598-0