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C1GALT1 high expression is associated with poor survival of patients with pancreatic ductal adenocarcinoma and promotes cell invasiveness through integrin α(v)

Pancreatic adenocarcinoma (PDAC) is a leading cause of cancer-related death. Altered glycosylation contributes to tumor progression and chemoresistance in many cancers. C1GALT1 is the key enzyme controlling the elongation of GalNAc-type O-glycosylation. Here we showed that C1GALT1 was overexpressed...

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Detalles Bibliográficos
Autores principales: Kuo, Ting-Chun, Wu, Ming-Hsun, Yang, Shih-Hung, Chen, Syue-Ting, Hsu, Tzu-Wen, Jhuang, Jie-Yang, Liao, Ying-Yu, Tien, Yu-Wen, Huang, Min-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892338/
https://www.ncbi.nlm.nih.gov/pubmed/33420364
http://dx.doi.org/10.1038/s41388-020-01594-4