Cargando…

C1GALT1 high expression is associated with poor survival of patients with pancreatic ductal adenocarcinoma and promotes cell invasiveness through integrin α(v)

Pancreatic adenocarcinoma (PDAC) is a leading cause of cancer-related death. Altered glycosylation contributes to tumor progression and chemoresistance in many cancers. C1GALT1 is the key enzyme controlling the elongation of GalNAc-type O-glycosylation. Here we showed that C1GALT1 was overexpressed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuo, Ting-Chun, Wu, Ming-Hsun, Yang, Shih-Hung, Chen, Syue-Ting, Hsu, Tzu-Wen, Jhuang, Jie-Yang, Liao, Ying-Yu, Tien, Yu-Wen, Huang, Min-Chuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892338/ https://www.ncbi.nlm.nih.gov/pubmed/33420364 http://dx.doi.org/10.1038/s41388-020-01594-4

Ejemplares similares

C1GALT1 is associated with poor survival and promotes soluble Ephrin A1-mediated cell migration through activation of EPHA2 in gastric cancer
por: Lee, Po-Chu, et al.
Publicado: (2020)

C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer
por: Lin, Mei-Chun, et al.
Publicado: (2018)

Silencing of MUC20 suppresses the malignant character of pancreatic ductal adenocarcinoma cells through inhibition of the HGF/MET pathway
por: Chen, Syue-Ting, et al.
Publicado: (2018)

C1GALT1 expression predicts a favorable prognosis and suppresses malignant phenotypes via TrkA signaling in neuroblastoma
por: Lin, Neng-Yu, et al.
Publicado: (2022)

Decreased B4GALT1 promotes hepatocellular carcinoma cell invasiveness by regulating the laminin-integrin pathway
por: Chen, Po-Da, et al.
Publicado: (2023)

Update on the role of C1GALT1 in cancer
por: Xia, Tong, et al.
Publicado: (2022)

C1GALT1 Promotes Invasive Phenotypes of Hepatocellular Carcinoma Cells by Modulating Integrin β1 Glycosylation and Activity
por: Liu, Chiung-Hui, et al.
Publicado: (2014)

Decreased LKB1 predicts poor prognosis in Pancreatic Ductal Adenocarcinoma
por: Yang, Jian-Yu, et al.
Publicado: (2015)

Contribution of nuclear BCL10 expression to tumor progression and poor prognosis of advanced and/or metastatic pancreatic ductal adenocarcinoma by activating NF-κB-related signaling
por: Kuo, Sung-Hsin, et al.
Publicado: (2021)

Corrigendum: Decreased LKB1 predicts poor prognosis in Pancreatic Ductal Adenocarcinoma
por: Yang, Jian-Yu, et al.
Publicado: (2015)

Betulinic Acid Affects the Energy-Related Proteomic Profiling in Pancreatic Ductal Adenocarcinoma Cells
por: Chiu, Ching-Feng, et al.
Publicado: (2021)

C1GALT1 in health and disease
por: Sun, Xiaojie, et al.
Publicado: (2021)

β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis
por: Giannini, Silvia, et al.
Publicado: (2020)

TMTC1 promotes invasiveness of ovarian cancer cells through integrins β1 and β4
por: Yeh, Ting-Chih, et al.
Publicado: (2023)

Plasminogen Activator Inhibitor 1 as a Poor Prognostic Indicator in Resectable Pancreatic Ductal Adenocarcinoma
por: Liu, Wen-Jing, et al.
Publicado: (2018)

Expression and Impact of C1GalT1 in Cancer Development and Progression
por: Wan, Yangu, et al.
Publicado: (2021)

Knockdown of C1GalT1 inhibits radioresistance of human esophageal cancer cells through modifying β1-integrin glycosylation
por: Zhang, Chuanyi, et al.
Publicado: (2018)

High expression of B4GALT1 is associated with poor prognosis in acute myeloid leukemia
por: Ren, Zhihong, et al.
Publicado: (2022)

Beta 1 integrin signaling mediates pancreatic ductal adenocarcinoma resistance to MEK inhibition
por: Brannon, Arthur, et al.
Publicado: (2020)

B4GALT5 high expression associated with poor prognosis of hepatocellular carcinoma
por: Han, Yang, et al.
Publicado: (2022)

The role of S100A9 in the interaction between pancreatic ductal adenocarcinoma cells and stromal cells
por: Kung, Pin-Jui, et al.
Publicado: (2021)

SMAD4 Loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells
por: Chen, Yu-Wen, et al.
Publicado: (2014)

High expression of RACK1 is associated with poor prognosis in patients with pancreatic ductal adenocarcinoma
por: Han, Hailin, et al.
Publicado: (2018)

Structural basis for the synthesis of the core 1 structure by C1GalT1
por: González-Ramírez, Andrés Manuel, et al.
Publicado: (2022)

Sp1 and COX2 expression is positively correlated with a poor prognosis in pancreatic ductal adenocarcinoma
por: Hang, Junjie, et al.
Publicado: (2016)

High expression FUT1 and B3GALT5 is an independent predictor of postoperative recurrence and survival in hepatocellular carcinoma
por: Kuo, Huan-Hsien, et al.
Publicado: (2017)

High expression of DDR1 is associated with the poor prognosis in Chinese patients with pancreatic ductal adenocarcinoma
por: Huo, Yanmiao, et al.
Publicado: (2015)

High B3GALT5 expression confers poor clinical outcome and contributes to tumor progression and metastasis in breast cancer
por: Liao, Yu-Mei, et al.
Publicado: (2021)

The Role of Exosomes in Pancreatic Ductal Adenocarcinoma Progression and Their Potential as Biomarkers
por: Hsu, Sheng-Kai, et al.
Publicado: (2023)

The Use of PET Imaging for Prognostic Integrin α(2)β(1) Phenotyping to Detect Non-Small Cell Lung Cancer and Monitor Drug Resistance Responses
por: Huang, Chiun-Wei, et al.
Publicado: (2017)

Review and Application of Integrin Alpha v Beta 6 in the Diagnosis and Treatment of Cholangiocarcinoma and Pancreatic Ductal Adenocarcinoma
por: Lian, Yunyu, et al.
Publicado: (2023)

B4GALT1 promotes immune escape by regulating the expression of PD-L1 at multiple levels in lung adenocarcinoma
por: Cui, Yanan, et al.
Publicado: (2023)

Targeting α4β7 integrin reduces mucosal transmission of SIV and protects GALT from infection
por: Byrareddy, Siddappa N., et al.
Publicado: (2014)

High expression of AFAP1-AS1 is associated with poor survival and short-term recurrence in pancreatic ductal adenocarcinoma
por: Ye, Yibiao, et al.
Publicado: (2015)

Interplays of glucose metabolism and KRAS mutation in pancreatic ductal adenocarcinoma
por: Liu, Yu-Huei, et al.
Publicado: (2022)

MCOLN1 Promotes Proliferation and Predicts Poor Survival of Patients with Pancreatic Ductal Adenocarcinoma
por: Hu, Zhan-Dong, et al.
Publicado: (2019)

High levels of serum glypican‐1 indicate poor prognosis in pancreatic ductal adenocarcinoma
por: Zhou, Cong‐ya, et al.
Publicado: (2018)

A Systematic Inflammation-based Model in Advanced Pancreatic Ductal Adenocarcinoma
por: Wu, Li-Xia, et al.
Publicado: (2019)

Simultaneous high expression of PLD1 and Sp1 predicts a poor prognosis for pancreatic ductal adenocarcinoma patients
por: Hu, Jiong, et al.
Publicado: (2016)

Two Hydroxyproline Galactosyltransferases, GALT5 and GALT2, Function in Arabinogalactan-Protein Glycosylation, Growth and Development in Arabidopsis
por: Basu, Debarati, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_vli9roijstuv2ub8ckb8pl1uei