Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene

BACKGROUND: Despite recent advances in the understanding of the genetic architecture of osteoarthritis (OA), only two genetic loci have been identified for OA of the hand, in part explained by the complexity of the different hand joints and heterogeneity of OA pathology. METHODS: We used data from t...

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Detalles Bibliográficos
Autores principales: Boer, Cindy Germaine, Yau, Michelle S, Rice, Sarah J, Coutinho de Almeida, Rodrigo, Cheung, Kathleen, Styrkarsdottir, Unnur, Southam, Lorraine, Broer, Linda, Wilkinson, Jeremy Mark, Uitterlinden, André G, Zeggini, Eleftheria, Felson, David, Loughlin, John, Young, Mariel, Capellini, Terence Dante, Meulenbelt, Ingrid, van Meurs, Joyce BJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Osteoarthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892373/
https://www.ncbi.nlm.nih.gov/pubmed/33055079
http://dx.doi.org/10.1136/annrheumdis-2020-217834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892373/
https://www.ncbi.nlm.nih.gov/pubmed/33055079
http://dx.doi.org/10.1136/annrheumdis-2020-217834

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