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Loss of Choline Agonism in the Inner Ear Hair Cell Nicotinic Acetylcholine Receptor Linked to the α10 Subunit

The α9α10 nicotinic acetylcholine receptor (nAChR) plays a fundamental role in inner ear physiology. It mediates synaptic transmission between efferent olivocochlear fibers that descend from the brainstem and hair cells of the auditory sensory epithelium. The α9 and α10 subunits have undergone a dis...

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Detalles Bibliográficos
Autores principales: Moglie, Marcelo J., Marcovich, Irina, Corradi, Jeremías, Carpaneto Freixas, Agustín E., Gallino, Sofía, Plazas, Paola V., Bouzat, Cecilia, Lipovsek, Marcela, Elgoyhen, Ana Belén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892445/
https://www.ncbi.nlm.nih.gov/pubmed/33613194
http://dx.doi.org/10.3389/fnmol.2021.639720