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Loss of Choline Agonism in the Inner Ear Hair Cell Nicotinic Acetylcholine Receptor Linked to the α10 Subunit
The α9α10 nicotinic acetylcholine receptor (nAChR) plays a fundamental role in inner ear physiology. It mediates synaptic transmission between efferent olivocochlear fibers that descend from the brainstem and hair cells of the auditory sensory epithelium. The α9 and α10 subunits have undergone a dis...
Autores principales: | Moglie, Marcelo J., Marcovich, Irina, Corradi, Jeremías, Carpaneto Freixas, Agustín E., Gallino, Sofía, Plazas, Paola V., Bouzat, Cecilia, Lipovsek, Marcela, Elgoyhen, Ana Belén |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892445/ https://www.ncbi.nlm.nih.gov/pubmed/33613194 http://dx.doi.org/10.3389/fnmol.2021.639720 |
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