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C-Terminal Amination of a Cationic Anti-Inflammatory Peptide Improves Bioavailability and Inhibitory Activity Against LPS-Induced Inflammation

Lipopolysaccharide (LPS) has been implicated as a major cause of inflammation and an uncontrolled LPS response increases the risk of localized inflammation and sepsis. While some native peptides are helpful in the treatment of LPS-induced inflammation, the use of these peptides is limited due to the...

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Detalles Bibliográficos
Autores principales: Zhang, Lulu, Wei, Xubiao, Zhang, Rijun, Koci, Matthew, Si, Dayong, Ahmad, Baseer, Guo, Henan, Hou, Yanfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892475/
https://www.ncbi.nlm.nih.gov/pubmed/33613547
http://dx.doi.org/10.3389/fimmu.2020.618312