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Dose-Finding Study of a CEA-Targeting Agent, SGM-101, for Intraoperative Fluorescence Imaging of Colorectal Cancer

BACKGROUND: Carcinoembryonic antigen is overexpressed in colorectal cancer (CRC), making it an optimal target for fluorescence imaging. A phase I/II study was designed to determine the optimal imaging dose of SGM-101 for intraoperative fluorescence imaging of primary and recurrent CRC. METHODS: Pati...

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Detalles Bibliográficos
Autores principales: de Valk, Kim S., Deken, Marion M., Schaap, Dennis P., Meijer, Ruben P., Boogerd, Leonora S., Hoogstins, Charlotte E., van der Valk, Maxime J., Kamerling, Ingrid M., Bhairosingh, Shadhvi S., Framery, Bérénice, Hilling, Denise E., Peeters, Koen C., Holman, Fabian A., Kusters, Miranda, Rutten, Harm J., Cailler, Françoise, Burggraaf, Jacobus, Vahrmeijer, Alexander L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892528/
https://www.ncbi.nlm.nih.gov/pubmed/33034788
http://dx.doi.org/10.1245/s10434-020-09069-2