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Dose-Finding Study of a CEA-Targeting Agent, SGM-101, for Intraoperative Fluorescence Imaging of Colorectal Cancer
BACKGROUND: Carcinoembryonic antigen is overexpressed in colorectal cancer (CRC), making it an optimal target for fluorescence imaging. A phase I/II study was designed to determine the optimal imaging dose of SGM-101 for intraoperative fluorescence imaging of primary and recurrent CRC. METHODS: Pati...
Autores principales: | de Valk, Kim S., Deken, Marion M., Schaap, Dennis P., Meijer, Ruben P., Boogerd, Leonora S., Hoogstins, Charlotte E., van der Valk, Maxime J., Kamerling, Ingrid M., Bhairosingh, Shadhvi S., Framery, Bérénice, Hilling, Denise E., Peeters, Koen C., Holman, Fabian A., Kusters, Miranda, Rutten, Harm J., Cailler, Françoise, Burggraaf, Jacobus, Vahrmeijer, Alexander L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892528/ https://www.ncbi.nlm.nih.gov/pubmed/33034788 http://dx.doi.org/10.1245/s10434-020-09069-2 |
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