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Relationship between CYP2D6 genotype, activity score and phenotype in a pediatric Thai population treated with risperidone
Recently, the Clinical Pharmacogenetics Implementation Consortium (CPIC) have revised recommendations for the translation of CYP2D6 genotype to phenotype. Changes affect phenotype grouping, as well as the value used to calculate activity score for the CYP2D6*10 allele to better reflect the substanti...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892547/ https://www.ncbi.nlm.nih.gov/pubmed/33603025 http://dx.doi.org/10.1038/s41598-021-83570-w |