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Isolation methodology is essential to the evaluation of the extracellular vesicle component of the senescence‐associated secretory phenotype

A hallmark of senescence is the acquisition of an enhanced secretome comprising inflammatory mediators and tissue remodelling agents – the senescence‐associated secretory phenotype (SASP). Through the SASP, senescent cells are hypothesised to contribute to both ageing and pathologies associated with...

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Detalles Bibliográficos
Autores principales: Wallis, Ryan, Josipovic, Natasa, Mizen, Hannah, Robles‐Tenorio, Arturo, Tyler, Eleanor J., Papantonis, Argyris, Bishop, Cleo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892802/
https://www.ncbi.nlm.nih.gov/pubmed/33659050
http://dx.doi.org/10.1002/jev2.12041