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The role of oxidised self-lipids and alveolar macrophage CD1b expression in COPD

In chronic obstructive pulmonary disease (COPD) apoptotic bronchial epithelial cells are increased, and their phagocytosis by alveolar macrophages (AM) is decreased alongside bacterial phagocytosis. Epithelial cellular lipids, including those exposed on uncleared apoptotic bodies, can become oxidize...

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Detalles Bibliográficos
Autores principales: Ween, Miranda P., White, Jake B., Tran, Hai B., Mukaro, Violet, Jones, Charles, Macowan, Matthew, Hodge, Gregory, Trim, Paul J., Snel, Marten F., Hodge, Sandra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892841/
https://www.ncbi.nlm.nih.gov/pubmed/33602992
http://dx.doi.org/10.1038/s41598-021-82481-0