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Autophagy buffers Ras-induced genotoxic stress enabling malignant transformation in keratinocytes primed by human papillomavirus

Malignant transformation involves an orchestrated rearrangement of cell cycle regulation mechanisms that must balance autonomic mitogenic impulses and deleterious oncogenic stress. Human papillomavirus (HPV) infection is highly prevalent in populations around the globe, whereas the incidence of cerv...

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Detalles Bibliográficos
Autores principales: Cararo-Lopes, Eduardo, Dias, Matheus H., da Silva, Marcelo S., Zeidler, Julianna D., Vessoni, Alexandre T., Reis, Marcelo S., Boccardo, Enrique, Armelin, Hugo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892846/
https://www.ncbi.nlm.nih.gov/pubmed/33602932
http://dx.doi.org/10.1038/s41419-021-03476-3