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Autophagy buffers Ras-induced genotoxic stress enabling malignant transformation in keratinocytes primed by human papillomavirus
Malignant transformation involves an orchestrated rearrangement of cell cycle regulation mechanisms that must balance autonomic mitogenic impulses and deleterious oncogenic stress. Human papillomavirus (HPV) infection is highly prevalent in populations around the globe, whereas the incidence of cerv...
Autores principales: | Cararo-Lopes, Eduardo, Dias, Matheus H., da Silva, Marcelo S., Zeidler, Julianna D., Vessoni, Alexandre T., Reis, Marcelo S., Boccardo, Enrique, Armelin, Hugo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892846/ https://www.ncbi.nlm.nih.gov/pubmed/33602932 http://dx.doi.org/10.1038/s41419-021-03476-3 |
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