Inflammation status modulates the effect of host genetic variation on intestinal gene expression in inflammatory bowel disease

More than 240 genetic risk loci have been associated with inflammatory bowel disease (IBD), but little is known about how they contribute to disease development in involved tissue. Here, we hypothesized that host genetic variation affects gene expression in an inflammation-dependent way, and investi...

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Detalles Bibliográficos
Autores principales: Hu, Shixian, Uniken Venema, Werna T., Westra, Harm-Jan, Vich Vila, Arnau, Barbieri, Ruggero, Voskuil, Michiel D., Blokzijl, Tjasso, Jansen, Bernadien H., Li, Yanni, Daly, Mark J., Xavier, Ramnik J., Dijkstra, Gerard, Festen, Eleonora A., Weersma, Rinse K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892863/
https://www.ncbi.nlm.nih.gov/pubmed/33602935
http://dx.doi.org/10.1038/s41467-021-21458-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892863/
https://www.ncbi.nlm.nih.gov/pubmed/33602935
http://dx.doi.org/10.1038/s41467-021-21458-z

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