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Sophisticated viral quasispecies with a genotype-related pattern of mutations in the hepatitis B X gene of HBeAg-ve chronically infected patients

Patients with HBeAg-negative chronic infection (CI) have not been extensively studied because of low viremia. The HBx protein, encoded by HBX, has a key role in viral replication. Here, we analyzed the viral quasispecies at the 5′ end of HBX in CI patients and compared it with that of patients in ot...

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Detalles Bibliográficos
Autores principales: Cortese, Maria Francesca, González, Carolina, Gregori, Josep, Casillas, Rosario, Carioti, Luca, Guerrero-Murillo, Mercedes, Riveiro-Barciela, Mar, Godoy, Cristina, Sopena, Sara, Yll, Marçal, Quer, Josep, Rando, Ariadna, Lopez-Martinez, Rosa, Pacín Ruiz, Beatriz, García-García, Selene, Esteban-Mur, Rafael, Tabernero, David, Buti, Maria, Rodríguez-Frías, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892877/
https://www.ncbi.nlm.nih.gov/pubmed/33603102
http://dx.doi.org/10.1038/s41598-021-83762-4