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Recent Advances in Metabolic Engineering, Protein Engineering, and Transcriptome-Guided Insights Toward Synthetic Production of Taxol

The diterpenoid paclitaxel (Taxol(®)) is a blockbuster anticancer agent that was originally isolated from the Pacific yew (Taxus brevifolia) five decades ago. Despite the wealth of information gained over the years on Taxol research, there still remains supply issues to meet increasing clinical dema...

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Detalles Bibliográficos
Autores principales: Mutanda, Ishmael, Li, Jianhua, Xu, Fanglin, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892896/
https://www.ncbi.nlm.nih.gov/pubmed/33614616
http://dx.doi.org/10.3389/fbioe.2021.632269