Cargando…

Molecular and Clinicopathological Characterization of a Prognostic Immune Gene Signature Associated With MGMT Methylation in Glioblastoma

Background: O6-methylguanine-DNA methyltransferase (MGMT) methylation status affects tumor chemo-resistance and the prognosis of glioblastoma (GBM) patients. We aimed to investigate the role of MGMT methylation in the regulation of GBM immunophenotype and discover an effective biomarker to improve p...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Liang, Zhang, Jiayue, Xuan, Shurui, Liu, Zhiyuan, Wang, Yu, Zhao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892978/
https://www.ncbi.nlm.nih.gov/pubmed/33614641
http://dx.doi.org/10.3389/fcell.2021.600506