Cargando…

Molecular and Clinicopathological Characterization of a Prognostic Immune Gene Signature Associated With MGMT Methylation in Glioblastoma

Background: O6-methylguanine-DNA methyltransferase (MGMT) methylation status affects tumor chemo-resistance and the prognosis of glioblastoma (GBM) patients. We aimed to investigate the role of MGMT methylation in the regulation of GBM immunophenotype and discover an effective biomarker to improve p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Liang, Zhang, Jiayue, Xuan, Shurui, Liu, Zhiyuan, Wang, Yu, Zhao, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892978/ https://www.ncbi.nlm.nih.gov/pubmed/33614641 http://dx.doi.org/10.3389/fcell.2021.600506

Ejemplares similares

Comprehensive Characterization of Alternative mRNA Splicing Events in Glioblastoma: Implications for Prognosis, Molecular Subtypes, and Immune Microenvironment Remodeling
por: Zhao, Liang, et al.
Publicado: (2021)

Systematic Characterization of Novel Immune Gene Signatures Predicts Prognostic Factors in Hepatocellular Carcinoma
por: Xu, Dafeng, et al.
Publicado: (2021)

Angiogenesis-Related Gene Signature-Derived Risk Score for Glioblastoma: Prospects for Predicting Prognosis and Immune Heterogeneity in Glioblastoma
por: Wang, Gang, et al.
Publicado: (2022)

DNA5mC Regulator-Mediated Molecular Clusters and Tumor Microenvironment Signatures in Glioblastoma
por: Yu, Xinyu, et al.
Publicado: (2022)

DNA Methylation Data-Based Classification and Identification of Prognostic Signature of Children With Wilms Tumor
por: Tang, Fucai, et al.
Publicado: (2021)

Ferroptosis Characterization in Lung Adenocarcinomas Reveals Prognostic Signature With Immunotherapeutic Implication
por: Sun, Sijin, et al.
Publicado: (2021)

Construction and Validation of a Cell Cycle-Related Robust Prognostic Signature in Colon Cancer
por: Zhang, Zhiyuan, et al.
Publicado: (2020)

Clinical Significance and Immune Landscape of a Pyroptosis-Derived LncRNA Signature for Glioblastoma
por: Xing, Zhe, et al.
Publicado: (2022)

Comprehensive Analysis of the Glycolysis-Related Gene Prognostic Signature and Immune Infiltration in Endometrial Cancer
por: Yang, Xiao, et al.
Publicado: (2022)

Hypoxia-immune-related microenvironment prognostic signature for osteosarcoma
por: Zhang, Wenshuo, et al.
Publicado: (2022)

Mapk14 is a Prognostic Biomarker and Correlates with the Clinicopathological Features and Immune Infiltration of Colorectal Cancer
por: Wang, Dan, et al.
Publicado: (2022)

A Prognostic Ferroptosis-Related lncRNAs Signature Associated With Immune Landscape and Radiotherapy Response in Glioma
por: Zheng, Jianglin, et al.
Publicado: (2021)

Identification and Validation of Immune- and Stemness-Related Prognostic Signature of Melanoma
por: Zhang, Yan, et al.
Publicado: (2021)

Molecular Characterization, Tumor Microenvironment Association, and Drug Susceptibility of DNA Methylation-Driven Genes in Renal Cell Carcinoma
por: Wang, Jinpeng, et al.
Publicado: (2022)

New Prognostic Gene Signature and Immune Escape Mechanisms of Bladder Cancer
por: Jiang, Yi, et al.
Publicado: (2022)

Identification of a Methylation-Regulating Genes Prognostic Signature to Predict the Prognosis and Aid Immunotherapy of Clear Cell Renal Cell Carcinoma
por: Zhang, Li, et al.
Publicado: (2022)

Identification of Hypoxia–Immune-Related Gene Signatures and Construction of a Prognostic Model in Kidney Renal Clear Cell Carcinoma
por: Bai, Shuheng, et al.
Publicado: (2022)

A three-gene signature for prognosis in patients with MGMT promoter-methylated glioblastoma
por: Wang, Wen, et al.
Publicado: (2016)

Tumor Immune Microenvironment Landscape in Glioma Identifies a Prognostic and Immunotherapeutic Signature
por: Zhang, Chunyu, et al.
Publicado: (2021)

Metabolism-Associated DNA Methylation Signature Stratifies Lower-Grade Glioma Patients and Predicts Response to Immunotherapy
por: Yang, Guozheng, et al.
Publicado: (2022)

Identification and validation of a prognostic risk model based on caveolin family genes for breast cancer
por: Tang, Qiang, et al.
Publicado: (2022)

Molecular Characterization of the Clinical and Tumor Immune Microenvironment Signature of 5-methylcytosine-Related Regulators in non-small Cell Lung Cancer
por: Liu, Taisheng, et al.
Publicado: (2021)

SUMOylation Regulator-Related Molecules Can Be Used as Prognostic Biomarkers for Glioblastoma
por: Li, Xiaozhi, et al.
Publicado: (2021)

Retinoic Acid Metabolism-Related Enzyme Signature Identified Prognostic and Immune Characteristics in Sarcoma
por: Xu, HuaiYuan, et al.
Publicado: (2022)

Tumor Microenvironment Profiling Identifies Prognostic Signatures and Suggests Immunotherapeutic Benefits in Neuroblastoma
por: Feng, Chenzhao, et al.
Publicado: (2022)

Combination of Immune-Related Genomic Alterations Reveals Immune Characterization and Prediction of Different Prognostic Risks in Ovarian Cancer
por: Zhao, Xibo, et al.
Publicado: (2021)

Radiomics and MGMT promoter methylation for prognostication of newly diagnosed glioblastoma
por: Sasaki, Takahiro, et al.
Publicado: (2019)

DNA Methylation Signature in Monozygotic Twins Discordant for Psoriatic Disease
por: Vecellio, Matteo, et al.
Publicado: (2021)

Identification and validation of the molecular subtype and prognostic signature for clear cell renal cell carcinoma based on neutrophil extracellular traps
por: Quan, Jing, et al.
Publicado: (2022)

Identification and Validation of Constructing the Prognostic Model With Four DNA Methylation-Driven Genes in Pancreatic Cancer
por: Chen, Guangyu, et al.
Publicado: (2022)

Development and Validation of a Hypoxia-Associated Prognostic Signature Related to Osteosarcoma Metastasis and Immune Infiltration
por: Fu, Yucheng, et al.
Publicado: (2021)

Identification of a Novel Prognostic Gene Signature From the Immune Cell Infiltration Landscape of Osteosarcoma
por: Fan, Lei, et al.
Publicado: (2021)

Development of an Oxidative Phosphorylation-Related and Immune Microenvironment Prognostic Signature in Uterine Corpus Endometrial Carcinoma
por: Liu, Jinhui, et al.
Publicado: (2021)

SUMOylation patterns and signature characterize the tumor microenvironment and predict prognosis in lung adenocarcinoma
por: Chen, Zhike, et al.
Publicado: (2023)

Integrating the Epigenome and Transcriptome of Hepatocellular Carcinoma to Identify Systematic Enhancer Aberrations and Establish an Aberrant Enhancer-Related Prognostic Signature
por: Huang, Peng, et al.
Publicado: (2022)

Location-Dependent DNA Methylation Signatures in a Clonal Invasive Crayfish
por: Tönges, Sina, et al.
Publicado: (2021)

Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone
por: Diboun, Ilhame, et al.
Publicado: (2022)

A five-miRNA signature with prognostic and predictive value for MGMT promoter-methylated glioblastoma patients
por: Cheng, Wen, et al.
Publicado: (2015)

Association between MGMT Enhancer Methylation and MGMT Promoter Methylation, MGMT Protein Expression, and Overall Survival in Glioblastoma
por: Zappe, Katja, et al.
Publicado: (2023)

Identification and Validation of a Novel Genomic Instability-Associated Long Non-Coding RNA Prognostic Signature in Head and Neck Squamous Cell Carcinoma
por: Chen, Yun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nbl91dqdkgoon6b300rvv3mfiv