Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection

Clostridioides difficile spores produced during infection are important for the recurrence of the disease. Here, we show that C. difficile spores gain entry into the intestinal mucosa via pathways dependent on host fibronectin-α(5)β(1) and vitronectin-α(v)β(1). The exosporium protein BclA3, on the s...

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Detalles Bibliográficos
Autores principales: Castro-Córdova, Pablo, Mora-Uribe, Paola, Reyes-Ramírez, Rodrigo, Cofré-Araneda, Glenda, Orozco-Aguilar, Josué, Brito-Silva, Christian, Mendoza-León, María José, Kuehne, Sarah A., Minton, Nigel P., Pizarro-Guajardo, Marjorie, Paredes-Sabja, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893008/
https://www.ncbi.nlm.nih.gov/pubmed/33602902
http://dx.doi.org/10.1038/s41467-021-21355-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893008/
https://www.ncbi.nlm.nih.gov/pubmed/33602902
http://dx.doi.org/10.1038/s41467-021-21355-5

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