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Human induced pluripotent stem cell-based platform for modeling cardiac ischemia

Ischemic heart disease is a major cause of death worldwide, and the only available therapy to salvage the tissue is reperfusion, which can initially cause further damage. Many therapeutics that have been promising in animal models have failed in human trials. Thus, functional human based cardiac isc...

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Detalles Bibliográficos
Autores principales: Häkli, Martta, Kreutzer, Joose, Mäki, Antti-Juhana, Välimäki, Hannu, Lappi, Henna, Huhtala, Heini, Kallio, Pasi, Aalto-Setälä, Katriina, Pekkanen-Mattila, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893031/
https://www.ncbi.nlm.nih.gov/pubmed/33603154
http://dx.doi.org/10.1038/s41598-021-83740-w